Drug Status in USA : Approved Drug Status in Canada : Approved
pronunciation
pronounced as (vi nor' el been)
Why is this medication prescribed?
Vinorelbine is used alone and in combination with other medications to treat certain types ofnon-small cell lung cancer that has spread to nearby tissues or to other parts of the body. Vinorelbine is in a class of medications called vinca alkaloids. It works by slowing or stopping the growth of cancer cells in your body.
How should this medicine be used?
Vinorelbine comes as a solution (liquid) to be injected intravenously (into a vein) by a doctor or nurse in a medical facility. It is usually given once a week. The length of treatment depends on how well your body responds to treatment with vinorelbine.
Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.
What are the precautions to be followed?
Before receiving vinorelbine,
tell your doctor and pharmacist if you are allergic to vinorelbine, any other medications, or any of the ingredients in vinorelbine injection. Ask your pharmacist for a list of the ingredients.
tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: certain antifungals such as itraconazole (Sporanox) and ketoconazole (Nizoral); clarithromycin (Biaxin, in Prevpac); HIV protease inhibitors including indinavir (Crixivan), nelfinavir (Viracept), and ritonavir (Norvir, in Kaletra); or nefazodone. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
tell your doctor if you are being treated with or have ever been treated with radiation therapy or cancer chemotherapy, or if you have or have ever had a disorder that affects your nerves or lung or liver disease.
Tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. You should not become pregnant or breastfeed while you are receiving vinorelbine injection. If you become pregnant while receiving vinorelbine injection, call your doctor. Vinorelbine may harm the fetus.
What are possible side effects of this medication ?
Vinorelbine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
nausea
vomiting
diarrhea
loss of appetite
weight loss
change in ability to taste food
sores in the mouth and throat
hearing loss
dizziness
headache
pain, numbness, burning, or tingling in the hands or feet
muscle, joint, or bone pain
hair loss
Some side effects can be serious. If you experience any of these symptoms or those listed in the IMPORTANT WARNING section, call your doctor immediately or get emergency medical treatment:
shortness of breath
cough
constipation
stomach pain
chest pain
irregular heartbeat
pale skin
unusual tiredness or weakness
unusual bleeding or bruising
hives
itching
rash
difficulty breathing or swallowing
Vinorelbine may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
How to store the medication and dispose it of after its use later?
Drug Category/Class
Antineoplastic Agents, Phytogenic
Vinca Alkaloids and Analogues
Antineoplastic Agents
Antineoplastic and Immunomodulating Agents
Combined Inhibitors of CYP3A4 and P-glycoprotein
Immunosuppressive Agents
CYP2D6 Inducers
CYP2D6 Inducers (strong)
CYP3A4 Inhibitors
Vinca alkaloids and analogues
Prescribed
For the treatment of non-small-cell lung carcinoma.