Trandolapril

Drug Status in USA : Approved
Drug Status in Canada : Approved

pronunciation

pronounced as (tran dole' a pril)

Why is this medication prescribed?

Trandolapril is used alone or in combination with other medications to treat high blood pressure. It is also used to improve survival in patients with heart failure after a heart attack. Trandolapril is in a class of medications called angiotensin-converting enzyme (ACE) inhibitors. It works by decreasing certain chemicals that tighten the blood vessels, so blood flows more smoothly and the heart can pump blood more efficiently.

High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys, and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medication, making lifestyle changes will also help to control your blood pressure. These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.


How should this medicine be used?

Trandolapril comes as a tablet to take by mouth. It is usually taken once or twice a day with or without food. To help you remember to take trandolapril, take it around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take trandolapril exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Your doctor will probably start you on a low dose of trandolapril and gradually increase your dose, not more than once a week.

Trandolapril controls high blood pressure but does not cure it. Continue to take trandolapril even if you feel well. Do not stop taking trandolapril without talking to your doctor.


What are the precautions to be followed?

Before taking trandolapril,
  • tell your doctor and pharmacist if you are allergic to trandolapril; other ACE inhibitors such as benazepril (Lotensin, in Lotrel), captopril (Capoten), enalapril (Vasotec, in Vaseretic), fosinopril (Monopril), lisinopril (in Prinzide, in Zestoretic), moexipril (Univasc, in Uniretic), perindopril (Aceon), quinapril (Accupril, in Accuretic, in Quinaretic), and ramipril (Altace); any other medications; or any ingredients in trandolapril tablets. Ask your pharmacist for a list of the ingredients.
  • tell your doctor if you have diabetes and you are taking aliskiren (Tekturna, in Amturnide, Tekamlo, Tekturna HCT). Your doctor will probably tell you not to take trandolapril if you have diabetes and you are also taking aliskiren.
  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention any of the following: diuretics ('water pills'); lithium (Lithobid); and potassium supplements. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor if you have recently had severe vomiting or diarrhea and if you have or have ever had heart, liver, or kidney disease; lupus; diabetes; or scleroderma (a condition in which extra tissue grows on the skin and some organs).
  • tell your doctor if you are breastfeeding.
  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking trandolapril.
  • you should know that diarrhea, vomiting, not drinking enough fluids, and sweating a lot can cause a drop in blood pressure, which may cause lightheadedness and fainting.

What are possible side effects of this medication ?

Trandolapril may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
  • cough
  • dizziness
  • muscle pain
Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:
  • swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
  • hoarseness
  • difficulty breathing or swallowing
  • yellowing of the skin or eyes
  • fever, sore throat, chills, and other signs of infection
  • lightheadedness
  • fainting

Trandolapril may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.


How to store the medication and dispose it of after its use later?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.


Drug Category/Class

  • Angiotensin-Converting Enzyme Inhibitors
  • Antihypertensive Agents
  • ACE Inhibitors, Plain
  • Agents Acting on the Renin-Angiotensin System
  • Cardiovascular System
  • ACE Inhibitors and Calcium Channel Blockers
  • ACE inhibitors, plain
  • ACE inhibitors and calcium channel blockers
Prescribed For the treatment of mild to moderate hypertension, as an adjunct in the treatment of congestive heart failure (CHF), to improve survival following...
Weight :430.5372
Structure Trandolapril
Generic Drug Trandolapril prescribed For the treatment of mild to moderate hypertension, as an adjunct in the treatment of congestive heart failure (CHF), to improve survival following...
Formula

C24H34N2O5

Trandolapril has 2 Brands listed


Zetpril (1 mg)Zetpril (2 mg)

Search Generic Drugs alphabetically