Probenecid Drug: Indication, Dosage, Precaution, Side Effect , Storage, Category Type and corresponding Brands - www.genericdrugscan.com

Probenecid

pronunciation

pronounced as (proe ben' e sid)

Why is this medication prescribed?

Probenecid is used to treat chronic gout and gouty arthritis. It is used to prevent attacks related to gout, not treat them once they occur. It acts on the kidneys to help the body eliminate uric acid. Probenecid is also used to make certain antibiotics more effective by preventing the body from passing them in the urine.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

How should this medicine be used?

Probenecid comes in a tablet to take by mouth. It usually is taken two times a day when prescribed for chronic gout or gouty arthritis and four times a day when prescribed with antibiotics to make them more effective. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take probenecid exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Probenecid may increase the frequency of gout attacks during the first 6 to 12 months that you take it, although it will eventually prevent them. Another drug, such as colchicine, may be prescribed to decrease this effect.

What are the precautions to be followed?

• tell your doctor and pharmacist if you are allergic to probenecid or any other drugs.
• tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially aminosalicylic acid, antibiotics, aspirin, cancer chemotherapy agents (methotrexate), clofibrate (Atromid-S), dapsone, diflunisal (Dolobid), diuretics ('water pills'), heparin, indomethacin (Indocin), medication for anxiety, nitrofurantoin (Macrodantin, Macrobid), oral diabetes medications, pyrazinamide, salsalate (Disalcid), and vitamins. Because aspirin products may affect the way your body responds to probenecid, you should avoid them while taking probenecid. If you need something to relieve minor pain or fever, ask your doctor or pharmacist to recommend an aspirin substitute, such as acetaminophen (Tylenol).
• tell your doctor if you have or have ever had ulcers, kidney stones, a kidney disorder, or a blood disorder.
• tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking probenecid, call your doctor immediately.
• tell your doctor if you plan to have surgery involving a general anesthetic.
• if you are having any urine tests done, tell your doctor and the laboratory personnel that you are taking probenecid because it may affect the results of the test.

What are possible side effects of this medication ?

• headache
• upset stomach
• vomiting
• loss of appetite
• dizziness

• severe skin rash
• difficulty breathing or swallowing
• unusual bleeding or bruising

How to store the medication and dispose it of after its use later?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

Drug Category/Class

• Adjuvants, Pharmaceutic
• Uricosuric Agents
• Antigout Preparations
• Preparations Increasing Uric Acid Excretion
• Cytochrome P-450 CYP2C8 Inhibitors
• Cytochrome P-450 CYP2C19 Inducers
• Cytochrome P-450 CYP2C8 Inducers
• CYP3A4 Inhibitors
• Musculo-Skeletal System
• Cytochrome P-450 CYP2C9 Inhibitors
• Cytochrome P-450 CYP2C9 Inducers
• Preparations increasing uric acid excretion

Prescribed	For the reduction of serum uric acid concentrations in chronic gouty arthritis and tophaceous gout in patients with frequent disabling gout attacks...
Weight :	285.359
Structure	Probenecid
Formula	C13H19NO4S

Probenecid has 1 Brands listed

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