Drug Status in USA : Approved Drug Status in Canada : Approved
pronunciation
pronounced as (ox a proe' zin)
Why is this medication prescribed?
Oxaprozin is used to relieve pain, tenderness, swelling, and stiffness caused by osteoarthritis (arthritis caused by a breakdown of the lining of the joints) and rheumatoid arthritis (arthritis caused by swelling of the lining of the joints). Oxaprozin is also used to relieve pain, tenderness, swelling, and stiffness caused by juvenile rheumatoid arthritis in children 6 years of age and older. Oxaprozin is in a class of medications called nonsteroidal anti-inflammatory medications (NSAIDs). It works by stopping the body's production of a substance that causes pain, fever, and inflammation.
How should this medicine be used?
Oxaprozin comes as a tablet to take by mouth. It is usually taken once or twice a day. Take oxaprozin at around the time(s) each day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take oxaprozin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
What are the precautions to be followed?
Before taking oxaprozin,
tell your doctor and pharmacist if you are allergic to oxaprozin, aspirin, or other NSAIDs such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn), any other medications, or any of the inactive ingredients in oxaprozin tablets. Ask your pharmacist for a list of the inactive ingredients.
tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: angiotensin-converting enzyme (ACE) inhibitors such as benazepril (Lotensin, in Lotrel), captopril, enalapril (Vasotec, in Vaseretic), fosinopril (Monopril), lisinopril (in Zestoretic), moexipril (Univasc), perindopril (Aceon, in Prestalia), quinapril (Accupril, in Quinaretic), ramipril (Altace), and trandolapril (Mavik, in Tarka); angiotensin receptor blockers (ARBs) such as azilsartan (Edarbi, in Edarbyclor), candesartan (Atacand, in Atacand HCT), eprosartan (Teveten), irbesartan (Avapro, in Avalide), losartan (Cozaar, in Hyzaar), olmesartan (Benicar, in Azor, in Benicar HCT, in Tribenzor), telmisartan (Micardis, in Micardis HCT, in Twynsta), and valsartan (in Exforge HCT); beta blockers such as atenolol (Tenormin, in Tenoretic), labetalol (Trandate), metoprolol (Lopressor, Toprol XL, in Dutoprol), nadolol (Corgard, in Corzide), and propranolol (Hemangeol, Inderal, Innopran); diuretics ('water pills'); glyburide (Glynase, Micronase); lithium (Lithobid); and methotrexate (Otrexup, Rasuvo, Trexall). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
tell your doctor if you have or ever had asthma, especially if you also have frequent stuffed or runny nose or nasal polyps; heart failure; swelling of the hands, feet, ankles, or lower legs; or kidney or liver disease.
tell your doctor if you are pregnant, especially if you are in the last few months of your pregnancy, you plan to become pregnant, or you are breastfeeding. If you become pregnant while taking oxaprozin, call your doctor.
talk to your doctor about the risks and benefits of taking oxaprozin if you are 65 years of age or older. Older adults should take lower doses of oxaprozin for only a short time period because higher doses used regularly may not be more effective and are more likely to cause serious side effects.
if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking oxaprozin.
plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen. Oxaprozin may make your skin sensitive to sunlight.
What are possible side effects of this medication ?
Oxaprozin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
diarrhea
constipation
vomiting
gas or bloating
drowsiness
difficulty sleeping
confusion
depression
dizziness
headache
ringing in the ears
Some side effects can be serious. If you experience any of the following symptoms or those mentioned in the IMPORTANT WARNING section, call your doctor immediately. Do not take any more oxaprozin until you speak to your doctor:
unexplained weight gain
shortness of breath or difficulty breathing
swelling in the abdomen, ankles, feet, or legs
fever
blisters
rash
itching
hives
swelling of the eyes, face, lips, tongue, throat, or hands
hoarseness
difficulty breathing or swallowing
yellowing of the skin or eyes
lack of energy
excessive tiredness
upset stomach
loss of appetite
pain in the upper right part of the stomach
flu-like symptoms
pale skin
fast heartbeat
cloudy, discolored, or bloody urine
back pain
difficult or painful urination
Oxaprozin may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
How to store the medication and dispose it of after its use later?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program.
Drug Category/Class
Anti-Inflammatory Agents, Non-Steroidal
Musculo-Skeletal System
Antiinflammatory and Antirheumatic Products, Non-Steroids
Antiinflammatory and Antirheumatic Products
Propionic Acid Derivatives
Cytochrome P-450 CYP2C9 Inhibitors
Cytochrome P-450 CYP2C9 Inducers
Propionic acid derivatives
Prescribed
Used to relieve the inflammation, swelling, stiffness, and joint pain associated with rheumatoid arthritis and osteoarthritis.