Orphenadrine

Drug Status in USA : Approved
Drug Status in Canada : Approved

pronunciation

pronounced as (or fen' a dreen)

Why is this medication prescribed?

Orphenadrine is used with rest, physical therapy, and other measures to relieve pain and discomfort caused by strains, sprains, and other muscle injuries. Orphenadrine is in a class of medications called skeletal muscle relaxants. It works by changing the way the body senses muscle pain.


How should this medicine be used?

Orphenadrine comes as a tablet and an extended-release (long-acting) tablet to take by mouth. It is usually taken twice a day. Try to take orphenadrine at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take orphenadrine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Swallow the extended-release tablets whole. do not split, chew, or crush them.


What are the precautions to be followed?

Before taking orphenadrine,
  • tell your doctor and pharmacist if you are allergic to orphenadrine,any other medications, or any of the ingredients in orphenadrine tablets or extended-release tablets.
  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: amantadine (Symadine, Symmetrel), fluphenazine (Prolixin), haloperidol (Haldol), medications for colds or allergies, medications for depression, perphenazine (Trilafon), prochlorperazine (Compazine), promethazine (Phenergan), sedatives, sleeping pills,and trifluoperazine (Stelazine). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor if you have or have ever had glaucoma; myasthenia gravis; ulcers; a urinary tract or intestinal blockage; an enlarged prostate; an irregular heartbeat; or liver, kidney, or heart disease.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking orphenadrine, call your doctor.
  • talk to your doctor about the risks and benefits of taking orphendrine if you are 65 years of age or older. Older adults should not usually take orphenadrine because it is not as safe as other medications that can be used to treat the same condition.
  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking orphenadrine.
  • you should know that this medication may make you drowsy. Do not drive a car or operate machinery until you know how orphenadine will affect you.
  • ask your doctor about the safe use of alcohol while you are taking this medication. Alcohol can make the side effects of orphenadrine worse.

What are possible side effects of this medication ?

Orphenadrine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
  • dry mouth
  • drowsiness
  • dizziness or lightheadedness
  • upset stomach
  • vomiting
  • constipation
  • difficulty urinating
  • blurred vision
  • headache
Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately:
  • fast or irregular heartbeat
  • fainting
  • confusion
  • hallucinations
  • skin rash

Orphenadrine may cause other side effects. Call your doctor if you experience any unusual problems during your treatment with orphenadrine.


How to store the medication and dispose it of after its use later?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.


Drug Category/Class

  • Antiparkinson Agents
  • Muscarinic Antagonists
  • Parasympatholytics
  • Muscle Relaxants, Skeletal
  • Anticholinergics
  • Ethers Chemically Close to Antihistamines
  • CYP2E1 Inhibitors
  • CYP2E1 Inducers
  • CYP2E1 Inducers (strong)
  • Antidyskinetics
  • Anti-Parkinson Drugs
  • Nervous System
  • Cytochrome P-450 CYP2B6 Inducers
  • Cytochrome P-450 CYP2B6 Inhibitors
  • CYP2B6 Inhibitors (strong)
  • CYP3A4 Inhibito
Prescribed Indicated for the treatment of Parkinson's disease.
Weight :269.3813
Structure Orphenadrine
Generic Drug Orphenadrine prescribed Indicated for the treatment of Parkinson
Formula

C18H23NO

Orphenadrine has 1 Brands listed


Orphipal (50 mg)

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