Drug Status in USA : Approved Drug Status in Canada : Approved
pronunciation
pronounced as (na byoo' me tone)
Why is this medication prescribed?
Nabumetone is used to relieve pain, tenderness, swelling, and stiffness caused by osteoarthritis (arthritis caused by a breakdown of the lining of the joints) and rheumatoid arthritis (arthritis caused by swelling of the lining of the joints). Nabumetone is in a class of medications called NSAIDs. It works by stopping the body's production of a substance that causes pain, fever, and inflammation.
How should this medicine be used?
Nabumetone comes as a tablet to take by mouth. It is usually taken once or twice a day with or without food. Take nabumetone at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take nabumetone exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Your doctor may start you on a low dose of nabumetone and gradually increase your dose.
What are the precautions to be followed?
Before taking nabumetone,
tell your doctor and pharmacist if you are allergic to nabumetone, aspirin or other NSAIDs such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn), or any other medications.
tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: angiotensin-converting enzyme (ACE) inhibitors such as benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), and trandolapril (Mavik); diuretics ('water pills'); lithium (Eskalith, Lithobid); oral medications for diabetes; phenytoin (Dilantin, Phenytek); and methotrexate (Rheumatrex). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
tell your doctor if you have or have ever had asthma, especially if you also have frequent stuffed or runny nose or nasal polyps (swelling of the lining of the nose); swelling of the hands, feet, ankles, or lower legs; or kidney or liver disease.
tell your doctor if you are pregnant, especially if you are in the last few months of your pregnancy, you plan to become pregnant, or you are breast-feeding. If you become pregnant while taking nabumetone, call your doctor.
if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking nabumetone.
plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen. Nabumetone may make your skin sensitive to sunlight.
What are possible side effects of this medication ?
Nabumetone may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
diarrhea
constipation
gas or bloating
dizziness
headache
dry mouth
sores in the mouth
nervousness
difficulty falling asleep or staying asleep
increased sweating
ringing in the ears
Some side effects can be serious. If you experience any of the following symptoms or those mentioned in the IMPORTANT WARNING section, call your doctor immediately. Do not take any more nabumetone until you speak to your doctor.
unexpected weight gain
yellowing of the skin or eyes
lack of energy
loss of appetite
nausea
pain in the upper right part of the stomach
flu-like symptoms
fever
blisters
rash
itching
hives
swelling of the eyes, face, lips, tongue, throat, arms, hands, feet ankles, or lower legs
difficulty breathing or swallowing
hoarseness
pale skin
fast heartbeat
cloudy, discolored, or bloody urine
back pain
difficult or painful urination
Nabumetone may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
How to store the medication and dispose it of after its use later?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
Drug Category/Class
Cyclooxygenase 2 Inhibitors
Cytochrome P-450 CYP1A2 Inhibitors
Cytochrome P-450 CYP1A2 Inducers
Antiinflammatory and Antirheumatic Products, Non-Steroids
Antiinflammatory and Antirheumatic Products
Musculo-Skeletal System
Other antiinflammatory and antirheumatic agents, non-steroids
Prescribed
For acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.