Linezolid

Drug Status in USA : Approved
Drug Status in Canada : Approved

pronunciation

pronounced as (li ne' zoh lid)

Why is this medication prescribed?

Linezolid is used to treat infections, including pneumonia, and infections of the skin and blood. Linezolid is in a class of antibacterials called oxazolidinones. It works by stopping the growth of bacteria. Antibiotics will not work for colds, flu, and other viral infections.


How should this medicine be used?

Linezolid comes as a tablet and oral suspension (liquid) to take by mouth. It is usually taken with or without food twice a day (every 12 hours) for 10 to 28 days. Children 11 years of age and younger usually take linezolid with or without food two to three times a day (every 8 to 12 hours) for 10 to 28 days. The length of your treatment depends on the type of infection you have. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take linezolid exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Before using the oral suspension, gently mix it by turning over the bottle three to five times. Do not shake the suspension.

Continue to take linezolid even if you feel well. Do not skip doses or stop taking linezolid without talking to your doctor. Take linezolid until you finish the prescription, even if you feel better. Stopping linezolid too soon may cause bacteria to become resistant to antibiotics.


What are the precautions to be followed?

Before taking linezolid,
  • tell your doctor and pharmacist if you are allergic to linezolid, any other medications, or any of the ingredients in the linezolid product you have been prescribed. Ask your pharmacist for a list of the ingredients .
  • tell your doctor if you are taking buspirone (Buspar); epinephrine (EpiPen); medications for migraine such as almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex), and zolmitriptan (Zomig); meperidine (Demerol); pseudoephedrine (Sudafed; in many cold or decongestant medications) selective serotonin reuptake inhibitors (SSRIs) such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, Symbyax), fluvoxamine (Luvox), paroxetine (Paxil), sertraline (Zoloft), and vilazodone (Vilbyrd); serotonin norepinephrine reuptake inhibitors (SNRIs) such as desvenlafaxine (Pristiq), duloxetine (Cymbalta), and venlafaxine (Effexor); and tricyclic antidepressants such as amitriptyline (Elavil), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Adapin, Sinequan), imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil). Also tell your doctor or pharmacist if you are taking the following medications or have stopped taking them within the past two weeks: isocarboxazid (Marplan) phenelzine (Nardil). rasagiline (Azilect), selegiline (Eldepryl), and tranylcypromine (Parnate). Your doctor will probably tell you not to take linezolid if you are taking one or more of these medications, or have taken them within the past two weeks.
  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: amphetamine (in Adderall); carbamazepine;phenylpropanolamine (no longer available in the US); dextroamphetamine (Adderall,Dexedrine, DextroStat); dexmethylphenidate (Focalin); lisdexamfetamine (Vyvanase); methamphetamine (Desoxyn); methylphenidate (Concerta, Metadate, Methylin, Ritalin); other antibiotics; phenobarbital; phenytoin (Dilantin, Phenytek); and rifampin (Rifadin,Rimactance, in Rifamate in Rifater ).Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with linezolid, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.
  • tell your doctor if you have carcinoid syndrome (a condition in which a tumor secretes serotonin). Your doctor will probably tell you not to take linezolid.
  • tell your doctor if you have or have ever had a chronic (long-lasting) infection, high blood pressure, hyperthyroidism (an overactive thyroid), immune suppression (problems with your immune system), pheochromocytoma (a tumor of the adrenal gland),seizures, or kidney disease.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking linezolid, call your doctor.
  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking linezolid.
  • if you have phenylketonuria (PKU, an inherited condition in which a special diet must be followed to prevent mental retardation), you should know that the oral suspension contains aspartame that forms phenylalanine.

What are possible side effects of this medication ?

Linezolid may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
  • diarrhea
  • headache
  • nausea
  • vomiting
  • stomach pain
  • difficulty falling asleep or staying asleep
  • dizziness
  • white patches in the mouth
  • change in color of the tongue
Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment:
  • hives
  • rash
  • itching
  • difficulty breathing or swallowing
  • swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
  • hoarseness
  • blisters or peeling skin
  • fever
  • loss of coordination
  • overactive reflexes
  • confusion, forgetfulness, or difficulty thinking
  • severe diarrhea (watery or bloody stools) that may occur with or without fever and stomach cramps (may occur up to 2 months or more after your treatment)
  • unusual bleeding or bruising
  • cough, chills, sore throat, and other signs of infection
  • changes in color vision, blurred vision, or other changes in vision
  • seizures

Linezolid may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.


How to store the medication and dispose it of after its use later?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from light and excess heat and moisture (not in the bathroom). Linezolid oral suspension should be used within 21 days.

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program.


Drug Category/Class

  • Protein Synthesis Inhibitors
  • Anti-Bacterial Agents
  • Antibacterials for Systemic Use
  • Antiinfectives for Systemic Use
  • Other antibacterials
Prescribed For the treatment of bacterial infections caused by susceptible strains of vancomycin resistant Enterococcus faecium, Staphylococcal aure...
Weight :337.3461
Structure Linezolid
Generic Drug Linezolid prescribed For the treatment of bacterial infections caused by susceptible strains of vancomycin resistant <i>Enterococcus faecium</i>, <i>Staphylococcal aure...
Formula

C16H20FN3O4

Linezolid has 61 Brands listed


AdizolidAdlid (300 ml)
Alzolid (300 ml)Alzolid (600 mg)
Arolid 600Bezolid
Entavar (300 ml)Entavar (600 mg)
Flyzid (600 mg)Infulid (600 mg)
Limet (600 mg)Linez (600 mg)
Linid (300 ml)Linid (600 mg)
LinoplusLinosept (300 ml)
Linosept (600 mg)Linospan (100 ml)
Linospan (300 ml)Linospan (600 mg)
Linospan DT (100 mg)Linox (100 ml)
Linox (300 ml)Linox (600 mg)
Lintran (600 mg)Lintran IV (300 ml)
Linvin (600 mg)Linzo (600 mg)
Linzobus DSLinzomind (600 mg)
Liolid InfLizbid (600 mg)
Lizemox FC (600 mg)Lizoforce (600 mg)
Lizoforce IV (300 ml)Lizogold
Lizolan (600 mg)Lizolid (600 mg)
Lizolid IV (100 ml)Lizolid IV (300 ml)
Lizomac (600 mg)Lizomed (600 mg)
Lizomed DS (30 ml)Lizostar (600 mg)
Lizotus 400 DTLizotus 600
Molzodin (600 mg)Multilid (600 mg)
OrcizolOzolid SR
RalinzSurelid
Topline (60 mg)Trezelot (300 ml)
Walibur (300 ml)Walibur (600 mg)
Xolid (300 ml)Xolid (600 mg)
Zodlin (600 mg)Zolidine (600 mg)
Zolimax (600 mg)

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