Rheumatoid arthritis, systemic lupus erythematosus. Prophylaxis and treatment of malaria.
Contraindication: What are the special precautions to be followed?
Under following conditions, use of this medication is inadvisable. Its use should be withhold as it would cause harm to the patient Retinal or visual field changes, known hypersensitivity. Long term use in children.
Other Precaution to be observed while taking this medication
Impairment liver or renal function, severe GI disorders, porphyria, psoriasis, neurological disorders especially a history of epilepsy, myasthenia gravis, G6PD deficiency, pregnancy, lactation. Monitor CBC in patients receiving prolonged therapy. Perform baseline and periodic 6 month eye exams, test periodically for muscle weakness.
What are possible side effects of this medication ?
Retinal or visual field changes, known hypersensitivity. Retinopathy, hair loss, photosensitivity, tinnitus, myopathy (long-term therapy). Psychosis, seizures, leucopenia and rarely aplastic anaemia, hepatitis, GI upsets, dizziness, hypokalaemia, headache, pruritus, urticaria, difficulty in visual accommodation. Loss of hair, bleaching or hair pigment, bluish-black pigmentation of the mucous membranes and skin, photosensitivity, tinnitus, reduced hearing, nerve deafness, neuromyopathy and myopathy, including cardiomyopathy.