Contraindication: What are the special precautions to be followed?
Under following conditions, use of this medication is inadvisable. Its use should be withhold as it would cause harm to the patient Insulin-dependent diabetes mellitus, diabetic coma, severe metabolic decompensationn (Keto acidosis) severe renal impairment, severe infection or trauma. Hypersensitivity. Pregnancy, lactation and paediatrics.
Other Precaution to be observed while taking this medication
Elderly, malnourished, mild to moderate renal and hepatic disorders. Impaired alertness. Avoid alcohol. Careful monitoring of blood-glucose concentration. Adrenocortical insufficiency. Avoid in severe hepatic impairment. Pregnancy and lactation.
What are possible side effects of this medication ?
Hypoglycaemia, cholestatic jaundice, agranulocytosis, aplastic anaemia, haemolytic anaemia. Blood dyscrasias (reversible), liver dysfunction, hypoglycaemia, GI symptoms, allergic skin reactions. Prolonged hypoglycaemia seen in elderly or debilitated patients with hepatic or renal diseases.