Fludarabine

Drug Status in USA : Approved
Drug Status in Canada : Approved

Indication : Why is this medication prescribed?

Chronic lymphocytic leukaemia.

Contraindication: What are the special precautions to be followed?

Under following conditions, use of this medication is inadvisable. Its use should be withhold as it would cause harm to the patient
Renal impairment, decompensated haemolytic anaemia. Pregnancy and lactation. Concomitant use of live vaccines.

Other Precaution to be observed while taking this medication

Routine monitoring of blood counts and Hb con. Monitor for signs of autoimmune haemolytic anaemia, elderly. Avoid contact with skin and eyes, avoid inhalation. Myelosuppression may be cumulative and severe increasing risk of opporutunistic infections. Increased risk of tumour lysis syndrome in patients with high tumour burden.

What are possible side effects of this medication ?

Myelosuppression (neutropenia, thrombocytopenia and anaemia), fever, chills and infection. Oedema, malaise, fatique, anorexia, nausea, vomiting and weakness.

Drug Category/Class

  • Purine analogues
  • Antineoplastic Agents
  • Immunosuppressive Agents
  • Antimetabolites
  • Antimetabolites, Antineoplastic
  • Antineoplastic and Immunomodulating Agents
  • Purine analogues
Prescribed For the treatment of adult patients with B-cell chronic lymphocytic leukemia (CLL) who have not responded to or whose disease has progressed during...
Weight :285.235
Structure Fludarabine
Generic Drug Fludarabine prescribed For the treatment of adult patients with B-cell chronic lymphocytic leukemia (CLL) who have not responded to or whose disease has progressed during...
Formula

C10H12FN5O4

Fludarabine has 5 Brands listed


Fludacel (10 mg)Fludacel (50 mg)
Fludara (10 mg)Fludara (50 mg)
Naprobin (50 mg)

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