Ezetimibe Drug: Indication, Dosage, Precaution, Side Effect , Storage, Category Type and corresponding Brands - www.genericdrugscan.com
Ezetimibe
Drug Status in USA : ApprovedDrug Status in Canada : Approved
pronunciation
pronounced as (e zet' i mibe)
Why is this medication prescribed?
Ezetimibe is used together with lifestyle changes (diet, weight-loss, exercise) to reduce the amount of cholesterol (a fat-like substance) and other fatty substances in the blood. It may be used alone or in combination with an HMG-CoA reductase inhibitor (statin). Ezetimibe is in a class of medications called cholesterol-lowering medications. It works by preventing the absorption of cholesterol in the intestine.
Buildup of cholesterol and fats along the walls of the blood vessels (a process known as atherosclerosis) decreases blood flow, which decreases the oxygen supply to the heart, brain, and other parts of the body. Lowering blood levels of cholesterol and fats may help reduce this buildup and may decrease your chances of developing heart conditions such as angina (chest pain), strokes, and heart attacks. Results of a clinical study that compared people who took ezetimibe and simvastatin with people who took simvastatin alone found that although the group of people taking ezetimibe and simvastatin had lower amounts of cholesterol in the blood, there was no difference between the two groups in the amount of cholesterol and fat buildup on the insides of the blood vessels in the neck. It is not currently understood why the additional lowering of cholesterol levels in the blood did not lead to a greater decrease in cholesterol and fat buildup along the walls of the blood vessels in people taking ezetimibe and simvastatin. Further studies are underway to compare treatment with ezetimibe and simvastatin to treatment with simvastatin alone to see if there is a difference in the risk of developing heart disease. Talk to your doctor if you have questions about the risks and benefits of treating increased amounts of cholesterol in your blood with ezetimibe and other medications.
In addition to taking a cholesterol-lowering medication, making certain changes in your daily habits can also lower your blood cholesterol levels. You should eat a diet that is low in saturated fat and cholesterol (see SPECIAL DIETARY); exercise 30 minutes on most, if not all, days; and lose weight if you are overweight.
How should this medicine be used?
Ezetimibe comes as a tablet to take by mouth. It is usually taken once a day with or without food. To help you remember to take ezetimibe, take it around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take ezetimibe exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Continue to take ezetimibe even if you feel well. Do not stop taking ezetimibe without talking to your doctor.
What are the precautions to be followed?
Before taking ezetimibe,- tell your doctor and pharmacist if you are allergic to ezetimibe or any other medications.
- tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention any of the following: anticoagulants (''blood thinners'') such as warfarin (Coumadin); cyclosporine (Neoral, Sandimmune); fenofibrate (TriCor); and gemfibrozil (Lopid). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- if you are taking cholestyramine (Questran), colesevelam (WellChol), or colestipol (Colestid), take it 4 hours before or 2 hours after ezetimibe.
- tell your doctor if you have or have ever had liver disease.
- tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking ezetimibe, call your doctor.
What are possible side effects of this medication ?
Ezetimibe may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:- headache
- dizziness
- diarrhea
- sore throat
- runny nose
- sneezing
- joint pain
- hives
- rash
- itching
- difficulty breathing or swallowing
- swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
- hoarseness
- upset stomach
- extreme tiredness
- unusual bleeding or bruising
- lack of energy
- loss of appetite
- pain in the upper right part of the stomach
- yellowing of the skin or eyes
- flu-like symptoms
- muscle pain or weakness
- fever
- chills
- pale or fatty stools
- chest pain
Ezetimibe may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
How to store the medication and dispose it of after its use later?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program.
Drug Category/Class
- Cholesterol Absorption Inhibitors
- Anticholesteremic Agents
- Lipid Modifying Agents, Plain
- Lipid Modifying Agents
- CYP3A4 Inhibitors
- Cardiovascular System
- Other lipid modifying agents
- HMG CoA reductase inhibitors in combination with other lipid modifying agents
| Prescribed | For use as adjunctive therapy to diet for the reduction of elevated total-C, LDL-C, and Apo B in patients with primary (heterozygous familial and n... |
| Weight : | 409.4252 |
| Structure | Ezetimibe |
 | |
| Formula | C24H21F2NO3 |
Ezetimibe has 17 Brands listed
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