Drug Status in USA : Approved Drug Status in Canada : Approved
pronunciation
pronounced as (daw'' noe roo' bi sin)
Why is this medication prescribed?
Daunorubicin is used with other chemotherapy drugs to treat a certain type of acute myeloid leukemia (AML; a type of cancer of the white blood cells). Daunorubicin is also used with other chemotherapy drugs to treat a certain type of acute lymphocytic leukemia (ALL; a type of cancer of the white blood cells). Daunorubicin is in a class of medications called anthracyclines. It works by slowing or stopping the growth of cancer cells in your body.
How should this medicine be used?
Daunorubicin comes as a solution (liquid) or as a powder to be mixed with liquid to be injected intravenously (into a vein) by a doctor or nurse in a medical facility along with other chemotherapy medications. When daunorubicin is used to treat AML, it is usually injected once a day on certain days of your treatment period. When daunorubicin is used to treat ALL, it is usually injected once a week. The length of treatment depends on the types of drugs you are taking, how well your body responds to them, and the type of cancer you have.
Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.
What are the precautions to be followed?
Before receiving daunorubicin injection,
tell your doctor and pharmacist if you are allergic to daunorubicin, any other medications, or any of the ingredients in daunorubicin injection. Ask your pharmacist for a list of the ingredients.
tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: azathioprine (Imuran), cyclosporine (Neoral, Sandimmune), methotrexate (Rheumatrex, Trexall), sirolimus (Rapamune), and tacrolimus (Prograf). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Other medications may also interact with daunorubicin, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.
tell your doctor if you have or have ever had any medical condition.
tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. You should not become pregnant while you are receiving daunorubicin injection. If you become pregnant while receiving daunorubicin, call your doctor. Daunorubicin may harm the fetus.
What are possible side effects of this medication ?
Daunorubicin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
nausea
vomiting
sores in the mouth and throat
diarrhea
stomach pain
hair loss
red urine
Some side effects can be serious. If you experience any of these symptoms or those listed in the IMPORTANT WARNING section, call your doctor immediately:
redness, pain, swelling, or burning at the site where the injection was given
rash
hives
itching
difficulty breathing or swallowing
Daunorubicin may increase the risk that you will develop other cancers. Talk to your doctor about the risks of taking this medication.
Daunorubicin may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
How to store the medication and dispose it of after its use later?
Drug Category/Class
Antibiotics, Antineoplastic
Antibiotics
Anthracyclines and Related Substances
Cytotoxic Antibiotics and Related Substances
Antineoplastic Agents
Antineoplastic and Immunomodulating Agents
Topoisomerase II Inhibitors
Cytochrome P-450 CYP1A2 Inhibitors
Cytochrome P-450 CYP1A2 Inducers
Combined Inhibitors of CYP3A4 and P-glycoprotein
Immunosuppressive Agents
CYP3A4 Inhibitors
Prescribed
For remission induction in acute nonlymphocytic leukemia (myelogenous, monocytic, erythroid) of adults and for remission induction in acute lymphoc...