Celecoxib

Drug Status in USA : Approved
Drug Status in Canada : Approved

pronunciation

pronounced as (sel'' e kox' ib)

Why is this medication prescribed?

Celecoxib is used to relieve pain, tenderness, swelling and stiffness caused by osteoarthritis (arthritis caused by a breakdown of the lining of the joints), rheumatoid arthritis (arthritis caused by swelling of the lining of the joints), and ankylosing spondylitis (arthritis that mainly affects the spine). It is also used to treat juvenile rheumatoid arthritis (a type of arthritis that affects children) in children 2 years of age and older. Celecoxib is also used to treat painful menstrual periods and to relieve other types of short-term pain including pain caused by injuries, surgery and other medical or dental procedures, or medical conditions that last for a limited time. Celecoxib is in a class of NSAIDs called COX-2 inhibitors. It works by stopping the body's production of a substance that causes pain and inflammation.


How should this medicine be used?

Celecoxib comes as a capsule to take by mouth. It is usually taken once or twice a day. If you are taking up to 200 mg of celecoxib at a time, you may take the medication with or without food. If you are taking more than 200 mg of celecoxib at a time, you should take the medication with food. Ask your doctor or pharmacist if you are not sure if you need to take your medication with food. To help you remember to take celecoxib, take it around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take celecoxib exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

If you cannot swallow the capsules or if you are giving this medication to a child, you may open the capsules and sprinkle the contents over a teaspoon of cold or room temperature applesauce. You may prepare the mixture in advance and store it for up to 6 hours in a refrigerator. When you are ready to take your medication, swallow all of the mixture. Then drink water to wash down the mixture and be sure that you have swallowed all of it.


What are the precautions to be followed?

Before taking celecoxib,
  • tell your doctor and pharmacist if you are allergic to celecoxib, aspirin or other NSAIDs such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn), sulfa medications, any other medications, or any of the inactive ingredients in celecoxib capsules. Ask your pharmacist for a list of the inactive ingredients.
  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: angiotensin-converting enzyme (ACE) inhibitors such as benazepril (Lotensin, in Lotrel), captopril, enalapril (Vasotec, in Vaseretic), fosinopril, lisinopril (in Zestoretic), moexipril (Univasc), perindopril (Aceon, in Prestalia), quinapril (Accupril, in Quinaretic), ramipril (Altace), and trandolapril (Mavik, in Tarka); angiotensin receptor blockers such as candesartan (Atacand, in Atacand HCT), eprosartan (Teveten), irbesartan (Avapro, in Avalide), losartan (Cozaar, in Hyzaar), olmesartan (Benicar, in Azor, in Benicar HCT, in Tribenzor), telmisartan (Micardis, in Micardis HCT, in Twynsta), and valsartan (in Exforge HCT); beta blockers such as atenolol (Tenormin, in Tenoretic), labetalol (Trandate), metoprolol (Lopressor, Toprol XL, in Dutoprol), nadolol (Corgard, in Corzide), and propranolol (Hemangeol, Inderal, Innopran); diuretics ('water pills'); fluconazole (Diflucan); and lithium (Lithobid). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor if you have or have ever had any of the conditions mentioned in the IMPORTANT WARNING section or asthma, especially if you also have frequent stuffed or runny nose or nasal polyps (swelling of the lining of the nose); swelling of the hands, arms, feet, ankles, or lower legs; heart failure; or liver or kidney disease.
  • tell your doctor if you are pregnant, especially if you are in the last few months of your pregnancy, you plan to become pregnant, or you are breast-feeding. If you become pregnant while taking celecoxib, call your doctor.
  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking celecoxib.

What are possible side effects of this medication ?

Celecoxib may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
  • diarrhea
  • gas or bloating
  • sore throat
  • cold symptoms
Some side effects can be serious. If you experience any of the following symptoms or those mentioned in the IMPORTANT WARNING section, call your doctor immediately. Do not take any more celecoxib until you speak to your doctor.
  • unexplained weight gain
  • shortness of breath or difficulty breathing
  • swelling of the abdomen, feet, ankles, or lower legs
  • nausea
  • excessive tiredness
  • unusual bleeding or bruising
  • itching
  • lack of energy
  • loss of appetite
  • pain in the upper right part of the stomach
  • yellowing of the skin or eyes
  • flu-like symptoms
  • blisters
  • fever
  • rash
  • hives
  • swelling of the face, throat, tongue, lips, eyes, or hands
  • hoarseness
  • difficulty swallowing or breathing
  • pale skin
  • fast heartbeat
  • cloudy, discolored, or bloody urine
  • back pain
  • difficult or painful urination
  • frequent urination, especially at night

Celecoxib may cause other side effects. Call your doctor if you have any unusual problems while you are taking this medication.


How to store the medication and dispose it of after its use later?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program.


Drug Category/Class

  • Coxibs
  • Antiinflammatory and Antirheumatic Products, Non-Steroids
  • Antiinflammatory and Antirheumatic Products
  • Cyclooxygenase 2 Inhibitors
  • Antineoplastic Agents
  • Antineoplastic and Immunomodulating Agents
  • Cytochrome P-450 CYP2C9 Inhibitors
  • Cytochrome P-450 CYP2C9 Inducers
  • Musculo-Skeletal System
  • CYP2D6 Inducers
  • CYP2D6 Inducers (strong)
  • CYP3A4 Inhibitors
  • Other antineoplastic ag
Prescribed For relief and management of osteoarthritis (OA), rheumatoid arthritis (RA), juvenile rheumatoid arthritis (JRA), ankylosing spondylitis, acute pai...
Weight :381.372
Structure Celecoxib
Generic Drug Celecoxib prescribed For relief and management of osteoarthritis (OA), rheumatoid arthritis (RA), juvenile rheumatoid arthritis (JRA), ankylosing spondylitis, acute pai...
Formula

C17H14F3N3O2S

Celecoxib has 49 Brands listed


Ce (100 mg)Ce (200 mg)
Celact (100 mg)Celact (200 mg)
Celact MD (200 mg)Celact-MD (100 mg)
Celcib (100 mg)Celcib (200 mg)
Celcox (100 mg)Celcox (200 mg)
Celebix (100 mg)Celebix (200 mg)
Celecap (100 mg)Celecap (200 mg)
Celedol (100 mg)Celedol (200 mg)
Celemax (200 mg)Celetop (100 mg)
Celetop (200 mg)Celexax (200 mg)
Celfast (100 mg)Celfast (200 mg)
Celib (100 mg)Celib (200 mg)
Celira (100 mg)Celira (200 mg)
Cobix (100 mg)Cobix (200 mg)
Colcibra (100 mg)Colcibra (200 mg)
Coxib (100 mg)Coxib (200 mg)
Eloxib (100 mg)Icel (100 mg)
Icel (200 mg)J Flex (100 mg)
J Flex (200 mg)Orthocel (100 mg)
Orthocel (200 mg)Revibra (100 mg)
Revibra (200 mg)Sionara (100 mg)
Sionara (200 mg)Speshel (100 mg)
Speshel (200 mg)Zecoxib (100 mg)
Zecoxib (200 mg)Zycel (100 mg)
Zycel (200 mg)

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