Drug Status in USA : Approved Drug Status in Canada : Approved
pronunciation
pronounced as (am loe' di peen)
Why is this medication prescribed?
Amlodipine is used alone or in combination with other medications to treat high blood pressure and chest pain (angina). Amlodipine is in a class of medications called calcium channel blockers. It lowers blood pressure by relaxing the blood vessels so the heart does not have to pump as hard. It controls chest pain by increasing the supply of blood to the heart. If taken regularly, amlodipine controls chest pain, but it does not stop chest pain once it starts. Your doctor may prescribe a different medication to take when you have chest pain.
High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medication, making lifestyle changes will also help to control your blood pressure. These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.
How should this medicine be used?
Amlodipine comes as a tablet to take by mouth. It is usually taken once a day. To help you remember to take amlodipine, take it around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take amlodipine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Your doctor will probably start you on a low dose of amlodipine and gradually increase your dose.
Amlodipine controls high blood pressure and chest pain (angina) but does not cure them. Continue to take amlodipine even if you feel well. Do not stop taking amlodipine without talking to your doctor.
What are the precautions to be followed?
Before taking amlodipine,
tell your doctor and pharmacist if you are allergic to amlodipine, any other medications, or any ingredients in amlodipine tablets. Ask your pharmacist for a list of the ingredients.
tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: certain medications for seizures such as carbamazepine (Carbatrol, Equetro, Tegretol), phenytoin (Dilantin, Phenytek), and phenobarbital; clarithromycin (Biaxin, in Prevpac); cyclosporine (Neoral, Sandimmune); efavirenz (Sustiva); indinavir (Crixivan); itraconazole (Onmel, Sporanox); ketoconazole (Nizoral); lovastatin (Altoprev, in Advicor); nefazodone;nelfinavir (Viracept); nevirapine (Viramune); rifabutin (Mycobutin); rifampin (Rifadin, Rimactane, in Rifamate), ritonavir (Norvir, in Kaletra), simvastatin (Zocor, in Simcor, in Vytorin), and tacrolimus (Astragraf SL, Prograf). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
tell your doctor if you have or have ever had heart failure or heart or liver disease.
tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking amlodipine, call your doctor.
What are possible side effects of this medication ?
Amlodipine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
swelling of the hands, feet, ankles, or lower legs
headache
upset stomach
stomach pain
dizziness or lightheadedness
drowsiness
excessive tiredness
flushing
Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment:
more frequent or more severe chest pain
rapid, pounding, or irregular heartbeat
fainting
How to store the medication and dispose it of after its use later?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
Drug Category/Class
Antihypertensive Agents
Antianginal Agents
Lipid Modifying Agents
Agents Acting on the Renin-Angiotensin System
Angiotensin II Antagonists and Calcium Channel Blockers
ACE Inhibitors and Calcium Channel Blockers
Renin-Inhibitors
Dihydropyridine Derivatives
Selective Calcium Channel Blockers With Mainly Vascular Effects
Calcium Channel Blockers and Diuretics
CYP2A6 Inhibitors
Prescribed
For the treatment of hypertension and chronic stable angina.